Proposition 65 Maximum Allowable Dose Level (MADL) for Reproductive Toxicity for Arsenic (Inorganic Oxides) for Oral Exposure May 2003 Office of Environmental Health Hazard Assessment Reproductive and Cancer Hazard Assessment Section Summary

The Proposition 65 listing of arsenic (inorganic oxides) was based on a finding by the Developmental and Reproductive Toxicant (DART) Identification Committee, the Proposition 65 State’s qualified experts for reproductive toxicity, that the chemicals had been clearly shown by scientifically valid testing according to generally accepted principles to cause developmental toxicity. As part of its deliberations, the Committee was provided with the document “Evidence on Developmental and Reproductive Toxicity of Arsenic,” developed by OEHHA (1996). OEHHA reviewed dose response data referenced that document as well as subsequent publications in preparation for MADL development.